N-(Adamantan-1-yl)-1,2,3,4-tetrahydroisoquinoline-2-carbothioamide
نویسندگان
چکیده
In the title compound, C20H26N2S, the N-containing six-membered ring adopts a boat conformation and the dihedral angle between the thio-carbamide group and the benzene ring is 49.67 (9)°. An intra-molecular C-H⋯S hydrogen bond generates an S(6) ring motif. The N-H group is sterically hindered and there are no significant inter-molecular inter-actions beyond van der Waals contacts.
منابع مشابه
trans-Tetrakis[N-(adamantan-1-yl)pyridine-4-carboxamide]dichloridomanganese(II)–N-(adamantan-1-yl)pyridine-4-carboxamide (1/2)
The asymmetric unit of the title compound, [MnCl(2)(C(16)H(20)N(2)O)(4)]·2C(16)H(20)N(2)O, is composed of two coordinating N-(adamantan-1-yl)pyridine-4-carboxamide mol-ecules, one Cl(-) anion, an Mn(II) ion, lying on an inversion centre, and one free N-(adamantan-1-yl)pyridine-4-carboxamide mol-ecule. The distorted octa-hedral Mn environment comprises two terminal Cl atoms and four monodentate ...
متن کاملDiscussion Word Count: 6,671 Abbreviations and definitions: ACPU, 1-(Adamantan-1-yl)-3-(1-(2-(7-hydroxy-2-oxo-2H-chromen- 4-yl)acetyl)piperidin-4-yl)urea; ARDS, Acute Respiratory Distress Syndrome; AUDA, 12-(3- Adamantan-1-yl-ureido)-dodecanoic acid; CDU, 1-cyclohexyl-3-dodecyl urea; ChEH, Cholesterol Epoxide Hydrolase; CMNPO, Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-
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N-(2-Hydroxybenzyl)adamantan-1-aminium 4-methylbenzenesulfonate
In the crystal structure of the title salt, C(17)H(24)NO(+)·C(7)H(7)O(3)S(-), the N-(2-hy-droxy-benz-yl)adamantan-1-aminium cations and 4-methyl-benzene-sulfonate anions are linked by O-H⋯O and N-H⋯O hydrogen bonds. C-H⋯π inter-actions are also observed between the cation and the anion.
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The asymmetric unit of the title dichloro-methane hemisolvate, C(24)H(33)N(5)S·0.5CH(2)Cl(2), comprises an adamantan-yl/triazole derivative and half a CH(2)Cl(2) mol-ecule of crystallization; the latter is disordered about a twofold axis of symmetry. The piperazine ring has a chair conformation and the two N-bound substituents occupy equatorial positions. The piperazine residue is almost normal...
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